Water → 6-bromo-N-(1-isopropyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine

HRID 819040Notes

Reaction equation

HRID 819040 reaction equation
[Br:10][c:11]1[n:12][c:13]([Br:20])[c:14]2[n:15]([cH:16]1)[cH:17][cH:18][n:19]2.[CH:1]([CH3:2])([CH3:3])[n:4]1[n:5][cH:6][c:7]([NH2:9])[cH:8]1.[CH:21]([N:22]([CH2:23][CH3:24])[CH:25]([CH3:26])[CH3:27])([CH3:28])[CH3:29].[O:31]=[CH:32][N:33]([CH3:34])[CH3:35].[OH2:30]>>[CH:1]([CH3:2])([CH3:3])[n:4]1[n:5][cH:6][c:7]([NH:9][c:13]2[n:12][c:11]([Br:10])[cH:16][n:15]3[c:14]2[n:19][cH:18][cH:17]3)[cH:8]1

Participants

6

Reactant 5

HCID 962WaterHCID 6228DimethylformamideHCID 81531DiisopropylethylamineHCID 134698261-(Propan-2-yl)-1H-pyrazol-4-amineHCID 150258436,8-Dibromoimidazo[1,2-a]pyrazine

Product 1

HCID 866424656-bromo-N-(1-isopropyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine

Sources & evidence

ORD record
ord-ded9c168209047e4966cd72b844e9815
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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