Chloroacetyl chloride → 2-chloro-N-(1-(3-fluorophenyl)-2-hydroxyethyl)acetamide
Reaction equation
[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[Cl:19][CH2:20][C:21](=[O:22])[Cl:23].[NH2:8][CH:9]([CH2:10][OH:11])[c:12]1[cH:13][c:14]([F:18])[cH:15][cH:16][cH:17]1>>[NH:8]([CH:9]([CH2:10][OH:11])[c:12]1[cH:13][c:14]([F:18])[cH:15][cH:16][cH:17]1)[C:21]([CH2:20][Cl:19])=[O:22]Participants
5
Sources & evidence
- ORD record
- ord-0403e6a4e7b44f1aa3e730d085b806f3
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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