Potassium Cation → 1-[4-(4-Chloro-2-fluoro-5-methoxyphenyl)-2-methylpiperazin-1-yl]-2-(3-iodopyrazolo[5,4-b]pyridin-1-yl)ethanone

HRID 819763Notes

Reaction equation

HRID 819763 reaction equation
[C:32](=[O:33])([O-:34])[O-:35].[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[Cl:1][CH2:2][C:3](=[O:4])[N:5]1[CH:6]([CH3:21])[CH2:7][N:8]([c:11]2[c:12]([F:20])[cH:13][c:14]([Cl:19])[c:15]([O:17][CH3:18])[cH:16]2)[CH2:9][CH2:10]1.[I:22][c:23]1[n:24][nH:25][c:26]2[n:27][cH:28][cH:29][cH:30][c:31]12.[K+:36].[K+:37].[O:38]=[CH:39][N:40]([CH3:41])[CH3:42]>>[CH2:2]([C:3](=[O:4])[N:5]1[CH:6]([CH3:21])[CH2:7][N:8]([c:11]2[c:12]([F:20])[cH:13][c:14]([Cl:19])[c:15]([O:17][CH3:18])[cH:16]2)[CH2:9][CH2:10]1)[n:25]1[n:24][c:23]([I:22])[c:31]2[c:26]1[n:27][cH:28][cH:29][cH:30]2

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 671040732-Chloro-1-[4-(4-chloro-2-fluoro-5-methoxy-phenyl)-2-methyl-piperazin-1-yl]-ethanoneHCID 178506575HCID 178506575, compound

Product 1

HCID 160063231-[4-(4-Chloro-2-fluoro-5-methoxyphenyl)-2-methylpiperazin-1-yl]-2-(3-iodopyrazolo[5,4-b]pyridin-1-yl)ethanone

Sources & evidence

ORD record
ord-9d71ed3686e740bfa8651d66eda7d693
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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