Dimethylformamide → Boc-D-hydroxyproline tert-butyl ester

HRID 820511Notes

Reaction equation

HRID 820511 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH:7]1[N:8]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:9][CH:10]([O:12][S:13]([CH3:14])(=[O:15])=[O:16])[CH2:11]1)=[O:24].[CH3:28][N:29]([CH3:30])[CH:31]=[O:32].[CH3:33][CH2:34][O:35][C:36](=[O:37])[CH3:38].[Na:25][C:26]#[N:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH:7]1[N:8]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:9][CH:10]([OH:12])[CH2:11]1)=[O:24]

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 178450761ditert-butyl 4-methylsulfonyloxypyrrolidine-1,2-dicarboxylateHCID 178511850HCID 178511850, compound

Product 1

HCID 18967914Boc-D-hydroxyproline tert-butyl ester

Sources & evidence

ORD record
ord-29d006fa897e409d83cfc2ce34880ba4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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