Toluene → N-(3-bromophenyl)-7-(1-piperidinylcarbonyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-amine

HRID 820741Notes

Reaction equation

[Br:11][c:12]1[cH:13][c:14]([NH:18][c:19]2[c:20]3[c:21]([n:22][cH:23][n:24]2)[s:25][c:26]2[c:27]3[CH2:28][CH2:29][CH:30]([C:32](=[O:33])[O:34][CH2:35][CH3:36])[CH2:31]2)[cH:15][cH:16][cH:17]1.[CH2:5]1[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]1.[CH3:1][Al:2]([CH3:3])[CH3:4].[CH3:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1>>[CH2:5]1[CH2:6][CH2:7][N:8]([C:32]([CH:30]2[CH2:29][CH2:28][c:27]3[c:20]4[c:19]([NH:18][c:14]5[cH:13][c:12]([Br:11])[cH:17][cH:16][cH:15]5)[n:24][cH:23][n:22][c:21]4[s:25][c:26]3[CH2:31]2)=[O:33])[CH2:9][CH2:10]1