Hydrochloric Acid → 7-Chloro-3-[(4-chloro-benzoylamino)-methyl]-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester

HRID 820795Notes

Reaction equation

HRID 820795 reaction equation
[CH3:2][O:3][C:4](=[O:5])[c:6]1[n:7](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[c:8]2[cH:9][c:10]([Cl:19])[cH:11][cH:12][c:13]2[c:14](=[O:18])[c:15]1[CH2:16][NH2:17].[CH:36]([N:37]([CH2:38][CH3:39])[CH:40]([CH3:41])[CH3:42])([CH3:43])[CH3:44].[Cl:26][C:27](=[O:28])[c:29]1[cH:30][cH:31][c:32]([Cl:33])[cH:34][cH:35]1.[Cl:45][CH2:46][Cl:47].[ClH:1]>>[CH3:2][O:3][C:4](=[O:5])[c:6]1[n:7](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[c:8]2[cH:9][c:10]([Cl:19])[cH:11][cH:12][c:13]2[c:14](=[O:18])[c:15]1[CH2:16][NH:17][C:27](=[O:28])[c:29]1[cH:30][cH:31][c:32]([Cl:33])[cH:34][cH:35]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 85014-Chlorobenzoyl chlorideHCID 81531DiisopropylethylamineHCID 71208533Methyl 3-(aminomethyl)-7-chloro-4-oxo-1-phenylquinoline-2-carboxylate

Product 1

HCID 712086617-Chloro-3-[(4-chloro-benzoylamino)-methyl]-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-05b06fb62aa84a5897e1091380ec548e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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