Sodium ion → 2-(4-(azidomethyl)-1H-imidazol-1-yl)-5-bromopyridine

HRID 821212Notes

Reaction equation

HRID 821212 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[cH:9][n:10][c:11]([CH2:13][OH:14])[cH:12]2)[n:6][cH:7]1.[CH3:24][C:25]#[N:26].[CH3:27][CH2:28][O:29][C:30]([CH3:31])=[O:32].[N-:19]=[N+:20]=[N-:21].[Na+:22].[OH2:23].[S:15]([Cl:16])([Cl:17])=[O:18]>>[Br:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[cH:9][n:10][c:11]([CH2:13][N:19]=[N+:20]=[N-:21])[cH:12]2)[n:6][cH:7]1

Participants

8

Reactant 7

HCID 923Sodium ionHCID 962WaterHCID 6342AcetonitrileHCID 8857Ethyl AcetateHCID 24386Thionyl ChlorideHCID 33558AzideHCID 68511931(1-(5-bromopyridin-2-yl)-1H-imidazol-4-yl)methanol

Product 1

HCID 866140062-(4-(azidomethyl)-1H-imidazol-1-yl)-5-bromopyridine

Sources & evidence

ORD record
ord-56cbbf92872e434ea3e7e7206c1be42b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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