Tetrahydrofuran → 5-Fluoro-2-phenylpyridine

HRID 821279Notes

Reaction equation

HRID 821279 reaction equation

[Br:1][c:2]1[n:3][cH:4][c:5]([F:8])[cH:6][cH:7]1.[Br:9][Mg:10][c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1.[CH3:22][CH2:23][O:24][C:25]([CH3:26])=[O:27].[O:17]1[CH2:18][CH2:19][CH2:20][CH2:21]1>>[c:2]1(-[c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[n:3][cH:4][c:5]([F:8])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 8028Tetrahydrofuran

HCID 8857Ethyl Acetate

HCID 27831712-Bromo-5-fluoropyridine

HCID 178418255HCID 178418255, compound

Product 1

HCID 463149355-Fluoro-2-phenylpyridine

Sources & evidence

ORD record: ord-d87431c85f424d089aca62948af74f92
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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