Dimethylformamide → 5-Chloro-2-methylbenzaldehyde

HRID 821745Notes

Reaction equation

[Br:1][c:2]1[c:3]([CH3:9])[cH:4][cH:5][c:6]([Cl:8])[cH:7]1.[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[CH3:10][CH2:11][CH2:12][CH2:13][Li:14].[O:15]=[CH:16][N:17]([CH3:18])[CH3:19]>>[c:2]1([CH:16]=[O:15])[c:3]([CH3:9])[cH:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 8028Tetrahydrofuran

HCID 6098982-Bromo-4-chloro-1-methylbenzene

HCID 178418339Butyllithium

Product 1

HCID 123475655-Chloro-2-methylbenzaldehyde

Sources & evidence

ORD record: ord-4200aa4ed9b24e98ac42406e9ffe5f62
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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