Hydrochloric Acid → 3-(4-Bromophenyl)piperidine

HRID 821764Notes

Reaction equation

HRID 821764 reaction equation
[BH3:20].[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[C:9](=[O:14])[NH:10][CH2:11][CH2:12][CH2:13]2)[cH:6][cH:7]1.[ClH:21].[O:15]1[CH2:16][CH2:17][CH2:18][CH2:19]1.[O:22]1[CH2:23][CH2:24][CH2:25][CH2:26]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][NH:10][CH2:11][CH2:12][CH2:13]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6331BoraneHCID 8028Tetrahydrofuran2×HCID 468400403-(4-Bromophenyl)piperidin-2-one

Product 1

HCID 468353263-(4-Bromophenyl)piperidine

Sources & evidence

ORD record
ord-5625633f25d94e25baef14d1e34bd251
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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