Trifluoroacetic acid → 2-(3-Bromo-phenyl)-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][c:8]2[c:13]([cH:14][cH:15]1)[NH:12][CH:11]([c:16]1[cH:17][c:18]([Br:22])[cH:19][cH:20][cH:21]1)[C:10]([CH3:23])([CH3:24])[CH:9]2[OH:25].[CH2:33]([SiH:34]([CH2:35][CH3:36])[CH2:37][CH3:38])[CH3:39].[OH:26][C:27]([C:28]([F:29])([F:30])[F:31])=[O:32]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][c:8]2[c:13]([cH:14][cH:15]1)[NH:12][CH:11]([c:16]1[cH:17][c:18]([Br:22])[cH:19][cH:20][cH:21]1)[C:10]([CH3:23])([CH3:24])[CH2:9]2Participants
4
Sources & evidence
- ORD record
- ord-94330528fed34ea2a4e59e5c0be88b1a
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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