HRID822145

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID962

Water

H2O

HCID13387

N-Methyl-2-pyrrolidone

C5H9NO

HCID81531

Diisopropylethylamine

C8H19N

HCID2758352

4,4-difluoropiperidine

C5H9F2N

HCID21192571

N-(4-Chlorobenzyl)-6-(chloromethyl)-1-methyl-4-oxo-1,4-dihydro-3-quinolinecarboxamide

C19H16Cl2N2O2

PRODUCTS

产物

HCID16073868

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-1ea738951d984c50a07c815f48140872
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应SMILES

[CH3:44][N:45]1[CH2:46][CH2:47][CH2:48][C:49]1=[O:50].[CH:26]([N:27]([CH2:28][CH3:29])[CH:30]([CH3:31])[CH3:32])([CH3:33])[CH3:34].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[c:10]2[cH:11][n:12]([CH3:23])[c:13]3[cH:14][cH:15][c:16]([CH2:21][Cl:22])[cH:17][c:18]3[c:19]2=[O:20])[cH:24][cH:25]1.[F:35][C:36]1([F:42])[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]1.[OH2:43]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[c:10]2[cH:11][n:12]([CH3:23])[c:13]3[cH:14][cH:15][c:16]([CH2:21][N:39]4[CH2:38][CH2:37][C:36]([F:35])([F:42])[CH2:41][CH2:40]4)[cH:17][c:18]3[c:19]2=[O:20])[cH:24][cH:25]1