Acetate → 5-Ethoxycarbonylmethylene-7-fluoro-1-oxo-1,3,4,5-tetrahydro-azepino[3,4-b]indole-2,10-dicarboxylic acid di-tert-butyl ester

HRID 822220Notes

Reaction equation

[C:20]([CH3:21])([CH3:22])([CH3:23])[O:24][C:25](=[O:26])[n:27]1[c:28]([C:38](=[O:39])[N:40]([CH2:41][CH2:42][CH:43]=[CH:44][C:45](=[O:46])[O:47][CH2:48][CH3:49])[C:50](=[O:51])[O:52][C:53]([CH3:54])([CH3:55])[CH3:56])[c:29]([I:37])[c:30]2[cH:31][c:32]([F:36])[cH:33][cH:34][c:35]12.[CH2:57]1[O:58][CH2:59][CH2:60][CH2:61]1.[O-:63][C:64]([CH3:65])=[O:66].[O-:67][C:68]([CH3:69])=[O:70].[Pd+2:62].[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[C:20]([CH3:21])([CH3:22])([CH3:23])[O:24][C:25](=[O:26])[n:27]1[c:28]2[c:29]([c:30]3[cH:31][c:32]([F:36])[cH:33][cH:34][c:35]13)[C:43](=[CH:44][C:45](=[O:46])[O:47][CH2:48][CH3:49])[CH2:42][CH2:41][N:40]([C:50](=[O:51])[O:52][C:53]([CH3:54])([CH3:55])[CH3:56])[C:38]2=[O:39]