Hydrochloric Acid → N,2-dimethoxy-N-methyl-2-(quinolin-5-yl)acetamide

HRID 822821Notes

Reaction equation

HRID 822821 reaction equation
[CH3:1][O:2][CH:3]([C:4](=[O:5])[OH:6])[c:7]1[c:8]2[cH:9][cH:10][cH:11][n:12][c:13]2[cH:14][cH:15][cH:16]1.[CH3:26][NH:27][O:28][CH3:29].[Cl:17][C:18]([O:19][CH2:20][CH:21]([CH3:22])[CH3:23])=[O:24].[Cl:30][CH2:31][Cl:32].[ClH:25]>>[CH3:1][O:2][CH:3]([C:4](=[O:6])[N:27]([CH3:26])[O:28][CH3:29])[c:7]1[c:8]2[cH:9][cH:10][cH:11][n:12][c:13]2[cH:14][cH:15][cH:16]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 14232N,O-DimethylhydroxylamineHCID 62365Isobutyl chloroformateHCID 584320332-Methoxy-2-(quinolin-5-yl)acetic acid

Product 1

HCID 58432006N,2-dimethoxy-N-methyl-2-(quinolin-5-yl)acetamide

Sources & evidence

ORD record
ord-2b9500c862a84e528d460e14e968c0a2
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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