Acetate → 6-(3-Methylpiperazinyl)-1-triisopropylsilyl-indole

HRID 822912Notes

Reaction equation

HRID 822912 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][cH:7][n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[c:9]2[cH:10]1.[CH3:21][CH:22]1[NH:23][CH2:24][CH2:25][NH:26][CH2:27]1.[CH3:28][C:29]([CH3:30])([O-:31])[CH3:32].[Na+:33].[O-:43][C:44]([CH3:45])=[O:46].[O-:47][C:48]([CH3:49])=[O:50].[Pd+2:42].[c:34]1([CH3:35])[c:36]([CH3:37])[cH:38][cH:39][cH:40][cH:41]1>>[c:2]1([N:26]2[CH2:25][CH2:24][NH:23][CH:22]([CH3:21])[CH2:27]2)[cH:3][cH:4][c:5]2[cH:6][cH:7][n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[c:9]2[cH:10]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 923Sodium ionHCID 7237O-XyleneHCID 660572-MethylpiperazineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 45749132-Methylpropan-2-olateHCID 129912436-bromo-1-(triisopropylsilyl)-1H-indole

Product 1

HCID 103392136-(3-Methylpiperazinyl)-1-triisopropylsilyl-indole

Sources & evidence

ORD record
ord-d523acfac0114134a6d189e36f9484a2
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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