Dimethylformamide → N-[2-(2,6-difluorophenyl)ethyl]-N'-(2-pyridyl)thiourea

HRID 823009Notes

Reaction equation

HRID 823009 reaction equation
[CH3:26][CH2:27][O:28][C:29](=[O:30])[CH3:31].[CH3:32][N:33]([CH3:34])[CH:35]=[O:36].[F:1][c:2]1[c:3]([CH2:9][CH2:10][NH2:11])[c:4]([F:8])[cH:5][cH:6][cH:7]1.[n:12]1[c:13]([NH:18][C:19](=[S:20])[n:21]2[cH:22][cH:23][n:24][cH:25]2)[cH:14][cH:15][cH:16][cH:17]1>>[F:1][c:2]1[c:3]([CH2:9][CH2:10][NH:11][C:19]([NH:18][c:13]2[n:12][cH:17][cH:16][cH:15][cH:14]2)=[S:20])[c:4]([F:8])[cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 37461112-(2,6-Difluorophenyl)ethan-1-amineHCID 197041381-[(2-Pyridyl)thiocarbamoyl]imidazole

Product 1

HCID 3001258N-[2-(2,6-difluorophenyl)ethyl]-N'-(2-pyridyl)thiourea

Sources & evidence

ORD record
ord-951887bec4ee4e37869a88e711755287
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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