Hydrochloric Acid → 4-(4-Hydroxyphenyl)-3-methyl-6h-isoxazolo[3,4-d]pyridazin-7-one

HRID 823346Notes

Reaction equation

HRID 823346 reaction equation
[CH2:20]([S-:21])[CH3:22].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10]3[c:11]([c:12](=[O:15])[nH:13][n:14]2)[n:16][o:17][c:18]3[CH3:19])[cH:7][cH:8]1.[ClH:25].[Na+:23].[O:26]=[CH:27][N:28]([CH3:29])[CH3:30].[OH2:24]>>[OH:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10]3[c:11]([c:12](=[O:15])[nH:13][n:14]2)[n:16][o:17][c:18]3[CH3:19])[cH:7][cH:8]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 962WaterHCID 6228DimethylformamideHCID 12688643ThioethoxideHCID 441218194-(4-methoxyphenyl)-3-methylisoxazolo[3,4-d]pyridazin-7(6H)-one

Product 1

HCID 1359822734-(4-Hydroxyphenyl)-3-methyl-6h-isoxazolo[3,4-d]pyridazin-7-one

Sources & evidence

ORD record
ord-3a9e6b7a5155408aa5728c060b598060
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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