Isopropanol → 5-Chloro-2-(4-morpholinophenylamino) quinazolin-8-ol
Reaction equation
[CH:27]([OH:28])([CH3:29])[CH3:30].[Cl:1][c:2]1[n:3][c:4]2[c:5]([OH:13])[cH:6][cH:7][c:8]([Cl:12])[c:9]2[cH:10][n:11]1.[O:14]1[CH2:15][CH2:16][N:17]([c:20]2[cH:21][cH:22][c:23]([NH2:24])[cH:25][cH:26]2)[CH2:18][CH2:19]1>>[c:2]1([NH:24][c:23]2[cH:22][cH:21][c:20]([N:17]3[CH2:16][CH2:15][O:14][CH2:19][CH2:18]3)[cH:26][cH:25]2)[n:3][c:4]2[c:5]([OH:13])[cH:6][cH:7][c:8]([Cl:12])[c:9]2[cH:10][n:11]1Participants
4
Sources & evidence
- ORD record
- ord-7f66a2ec803d492f85d7f573d8569fad
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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