4-Hydroxybenzaldehyde → 2-Chloro-4-(4-formylphenoxy)benzonitrile

HRID 823964Notes

Reaction equation

HRID 823964 reaction equation
[Cl:10][c:11]1[c:12]([C:13]#[N:14])[cH:15][cH:16][c:17]([F:19])[cH:18]1.[K+:20].[K+:21].[O-:22][C:23]([O-:24])=[O:25].[O:27]=[CH:28][N:29]([CH3:30])[CH3:31].[OH2:26].[OH:1][c:2]1[cH:3][cH:4][c:5]([CH:6]=[O:7])[cH:8][cH:9]1>>[O:1]([c:2]1[cH:3][cH:4][c:5]([CH:6]=[O:7])[cH:8][cH:9]1)[c:17]1[cH:16][cH:15][c:12]([C:13]#[N:14])[c:11]([Cl:10])[cH:18]1

Participants

7

Reactant 6

HCID 1264-HydroxybenzaldehydeHCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 1090002-Chloro-4-fluorobenzonitrile

Product 1

HCID 597300142-Chloro-4-(4-formylphenoxy)benzonitrile

Sources & evidence

ORD record
ord-33c75768f11f43ecac21ad1f55b7ff5e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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