Sodium ion → 4-(4-Chloro-phenyl)-1H-indole

HRID 824176Notes

Reaction equation

HRID 824176 reaction equation
[Br:19][c:20]1[cH:21][cH:22][c:23]([Cl:26])[cH:24][cH:25]1.[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:1][C:2]1([CH3:3])[C:4]([CH3:5])([CH3:6])[O:7][B:8]([c:9]2[c:10]3[cH:11][cH:12][nH:13][c:14]3[cH:15][cH:16][cH:17]2)[O:18]1.[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[Na+:28].[OH-:27].[Pd:34]>>[c:9]1(-[c:20]2[cH:21][cH:22][c:23]([Cl:26])[cH:24][cH:25]2)[c:10]2[cH:11][cH:12][nH:13][c:14]2[cH:15][cH:16][cH:17]1

Participants

8

Reactant 7

HCID 923Sodium ionHCID 961HydroxideHCID 7806p-BromochlorobenzeneHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 23938PalladiumHCID 113224711H-Indole-4-boronic acid, pinacol ester

Product 1

HCID 225617474-(4-Chloro-phenyl)-1H-indole

Sources & evidence

ORD record
ord-c1edd9dde6034645be1f1aefef40f5ff
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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