Dimethylformamide → 1-(4-Chloropyrimidin-2-yl)pyrrolidin-3-ol

HRID 824583Notes

Reaction equation

HRID 824583 reaction equation
[O:19]=[CH:20][N:21]([CH3:22])[CH3:23].[OH:1][CH:2]1[CH2:3][N:4]([c:7]2[n:8][cH:9][cH:10][c:11]([OH:13])[n:12]2)[CH2:5][CH2:6]1.[P:14]([Cl:15])([Cl:16])([Cl:17])=[O:18]>>[OH:1][CH:2]1[CH2:3][N:4]([c:7]2[n:8][cH:9][cH:10][c:11]([Cl:16])[n:12]2)[CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24813Phosphorus oxychlorideHCID 178516515HCID 178516515, compound

Product 1

HCID 457875341-(4-Chloropyrimidin-2-yl)pyrrolidin-3-ol

Sources & evidence

ORD record
ord-1c0971798761491688f2210bb8a77160
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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