Triethylamine → 2-(3-methyl-1-(2,2,2-trifluoroethyl)-1H-1,2,4-triazol-5-yl)-9-(2-(2-methylbenzyl)pyrrolidin-1-yl)-5,6-dihydroimidazo[1,2-d]pyrido[3,4-f][1,4]oxazepine

HRID 824631Notes

Reaction equation

HRID 824631 reaction equation
[CH3:27][c:28]1[c:29]([CH2:30][CH:31]2[NH:32][CH2:33][CH2:34][CH2:35]2)[cH:36][cH:37][cH:38][cH:39]1.[CH3:40][N:41]1[CH2:42][CH2:43][CH2:44][C:45]1=[O:46].[CH3:47][CH2:48][N:49]([CH2:50][CH3:51])[CH2:52][CH3:53].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([cH:25][n:26]1)-[c:6]1[n:7][c:8](-[c:14]3[n:15]([CH2:20][C:21]([F:22])([F:23])[F:24])[n:16][c:17]([CH3:19])[n:18]3)[cH:9][n:10]1[CH2:11][CH2:12][O:13]2>>[c:2]1([N:32]2[CH:31]([CH2:30][c:29]3[c:28]([CH3:27])[cH:39][cH:38][cH:37][cH:36]3)[CH2:35][CH2:34][CH2:33]2)[cH:3][c:4]2[c:5]([cH:25][n:26]1)-[c:6]1[n:7][c:8](-[c:14]3[n:15]([CH2:20][C:21]([F:22])([F:23])[F:24])[n:16][c:17]([CH3:19])[n:18]3)[cH:9][n:10]1[CH2:11][CH2:12][O:13]2

Participants

5

Reactant 4

HCID 8471TriethylamineHCID 13387N-methyl-2-pyrrolidoneHCID 39017062-((2-Methylphenyl)methyl)pyrrolidineHCID 866523128-Chloro-2-[5-methyl-2-(2,2,2-trifluoro-ethyl)-2H-[1,2,4]triazol-3-yl]-4,5-dihydro-6-oxa-1,3a,9-triaza-benzo[e]azulene

Product 1

HCID 683933702-(3-methyl-1-(2,2,2-trifluoroethyl)-1H-1,2,4-triazol-5-yl)-9-(2-(2-methylbenzyl)pyrrolidin-1-yl)-5,6-dihydroimidazo[1,2-d]pyrido[3,4-f][1,4]oxazepine

Sources & evidence

ORD record
ord-89cb5ed3102b46fea2e5eccde60c4c32
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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