Tetrahydrofuran → Methyl 2-(4-chloro-2,6-dimethylphenoxy)-4-(4-ethyl-2-oxo-1,3-oxazolidin-3-yl)-6-methylpyridine-3-carboxylate

HRID 824825Notes

Reaction equation

HRID 824825 reaction equation
[CH2:35]1[CH2:37][CH2:36][CH2:38][O:39]1.[CH3:1][O:2][C:3]([c:4]1[c:5]([O:17][c:18]2[c:19]([CH3:26])[cH:20][c:21]([Cl:25])[cH:22][c:23]2[CH3:24])[n:6][c:7]([CH3:16])[cH:8][c:9]1[NH:10][CH:11]([CH2:12][CH3:13])[CH2:14][OH:15])=[O:27].[CH3:28][CH2:29][N:30]([CH2:31][CH3:32])[CH2:33][CH3:34]>>[CH3:1][O:2][C:3]([c:4]1[c:5]([O:17][c:18]2[c:19]([CH3:26])[cH:20][c:21]([Cl:25])[cH:22][c:23]2[CH3:24])[n:6][c:7]([CH3:16])[cH:8][c:9]1[N:10]1[CH:11]([CH2:12][CH3:13])[CH2:14][O:15][C:38]1=[O:39])=[O:27]

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 101786472-(4-Chloro-2,6-dimethyl-phenoxy)-4-(1-hydroxymethyl-propylamino)-6-methyl-nicotinic acid methyl ester

Product 1

HCID 69587549Methyl 2-(4-chloro-2,6-dimethylphenoxy)-4-(4-ethyl-2-oxo-1,3-oxazolidin-3-yl)-6-methylpyridine-3-carboxylate

Sources & evidence

ORD record
ord-31eb76f5b7b44326b9cbae6c515816b2
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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