Potassium Cation → Methyl 5-ethynylnicotinate

HRID 825129Notes

Reaction equation

HRID 825129 reaction equation

[Br:1][c:2]1[cH:3][n:4][cH:5][c:6]([C:7](=[O:8])[O:9][CH3:10])[cH:11]1.[C:12](#[CH:13])[Si:14]([CH3:15])([CH3:16])[CH3:17].[C:18](=[O:19])([O-:20])[O-:21].[Cu:24][I:25].[K+:22].[K+:23]>>[c:2]1([C:12]#[CH:13])[cH:3][n:4][cH:5][c:6]([C:7](=[O:8])[O:9][CH3:10])[cH:11]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×

HCID 19660Carbonate Ion

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

HCID 66111Trimethylsilylacetylene

HCID 699336Methyl 5-bromopyridine-3-carboxylate

Product 1

HCID 53898384Methyl 5-ethynylnicotinate

Sources & evidence

ORD record: ord-f99195e136a94f7ba0652c1a5e9b231f
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…