Tetrahydrofuran → N-(6-chloro-5-phenyl-1H-indazol-3-yl)butanamide

HRID 825471Notes

Reaction equation

HRID 825471 reaction equation
[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[CH3:49][CH2:50][O:51][C:52](=[O:53])[CH3:54].[F-:1].[O:55]1[CH2:56][CH2:57][CH2:58][CH2:59]1.[c:19]1(-[c:25]2[cH:26][c:27]3[c:28]([NH:43][C:44]([CH2:45][CH2:46][CH3:47])=[O:48])[n:29][n:30]([CH2:35][O:36][CH2:37][CH2:38][Si:39]([CH3:40])([CH3:41])[CH3:42])[c:31]3[cH:32][c:33]2[Cl:34])[cH:20][cH:21][cH:22][cH:23][cH:24]1>>[c:19]1(-[c:25]2[cH:26][c:27]3[c:28]([NH:43][C:44]([CH2:45][CH2:46][CH3:47])=[O:48])[n:29][nH:30][c:31]3[cH:32][c:33]2[Cl:34])[cH:20][cH:21][cH:22][cH:23][cH:24]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 22319494N-[5-phenyl-6-chloro 1-[(2-trimethylsilylethoxy)methyl]indazol-3-yl]butanamide

Product 1

HCID 22319604N-(6-chloro-5-phenyl-1H-indazol-3-yl)butanamide

Sources & evidence

ORD record
ord-f4216ba640ce4b87ba5d89f3ed483a16
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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