Dichloromethane → 2-Chloro-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-isonicotinamide

HRID 826384Notes

Reaction equation

HRID 826384 reaction equation
[CH2:19]([N:20]([CH:21]([CH3:22])[CH3:23])[CH:24]([CH3:25])[CH3:26])[CH3:27].[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:7]2[c:8]1[n:9][c:10]([NH2:12])[s:11]2.[Cl:28][c:29]1[cH:30][c:31]([C:32](=[O:33])[Cl:34])[cH:35][cH:36][n:37]1.[Cl:43][CH2:44][Cl:45]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:7]2[c:8]1[n:9][c:10]([NH:12][C:32]([c:31]1[cH:30][c:29]([Cl:28])[n:37][cH:36][cH:35]1)=[O:33])[s:11]2

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 81531DiisopropylethylamineHCID 28000032-Chloropyridine-4-carbonyl chlorideHCID 114028614-Methoxy-7-morpholinobenzo[d]thiazol-2-amine

Product 1

HCID 113156942-Chloro-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-isonicotinamide

Sources & evidence

ORD record
ord-346cea4693474c3aaa95ed7486e8b51d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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