Acetate → 3-[3-[2-(1,3-Dioxolan-2-yl)-4-methoxyphenyl]prop-2-enoyl]-4-phenyl-1,3-oxazolidin-2-one

HRID 826686Notes

Reaction equation

HRID 826686 reaction equation
[Br:1][c:2]1[c:3]([CH:10]2[O:11][CH2:12][CH2:13][O:14]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[C:15]([CH:16]=[CH2:17])(=[O:18])[N:19]1[C:20](=[O:30])[O:21][CH2:22][CH:23]1[c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1.[C:60]([O-:61])(=[O:62])[CH3:63].[C:65]([O-:66])(=[O:67])[CH3:68].[CH3:53][CH2:54][N:55]([CH2:56][CH3:57])[CH2:58][CH3:59].[Pd+2:64].[c:31]1([CH3:32])[cH:33][cH:34][cH:35][cH:36][c:37]1[P:38]([c:39]1[cH:40][cH:41][cH:42][cH:43][c:44]1[CH3:45])[c:46]1[cH:47][cH:48][cH:49][cH:50][c:51]1[CH3:52]>>[c:2]1([CH:17]=[CH:16][C:15](=[O:18])[N:19]2[C:20](=[O:30])[O:21][CH2:22][CH:23]2[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:3]([CH:10]2[O:11][CH2:12][CH2:13][O:14]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 175Acetate2×HCID 8471TriethylamineHCID 80271Tri-o-tolylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 111845031,3-Dioxolane, 2-(2-bromo-5-methoxyphenyl)-HCID 146567794-Phenyl-3-prop-2-enoyl-1,3-oxazolidin-2-one

Product 1

HCID 669115783-[3-[2-(1,3-Dioxolan-2-yl)-4-methoxyphenyl]prop-2-enoyl]-4-phenyl-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-f6cf3bddba8944cf89478d04b1a09c77
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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