Tetrahydrofuran → 6-Hydroxymethylindole

HRID 826707Notes

Reaction equation

[Al+3:14].[H-:13].[H-:16].[H-:17].[H-:18].[Li+:15].[O:19]1[CH2:20][CH2:21][CH2:22][CH2:23]1.[nH:1]1[cH:2][cH:3][c:4]2[cH:5][cH:6][c:7]([C:10](=[O:11])[OH:12])[cH:8][c:9]12>>[nH:1]1[cH:2][cH:3][c:4]2[cH:5][cH:6][c:7]([CH2:10][OH:11])[cH:8][c:9]12

Participants

Reactant 5

HCID 8028Tetrahydrofuran

HCID 28486Lithium ion

HCID 104727Aluminum Cation

HCID 166653Hydride4×

HCID 5952301H-indole-6-carboxylic acid

Product 1

HCID 27734596-Hydroxymethylindole

Sources & evidence

ORD record: ord-b6df8710008144af9b77c47c94b351c2
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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