Sodium ion → 3-Bromo-2-(2,2,2-trifluoroethoxy)-5-(trifluoromethyl)pyridine

HRID 826842Notes

Reaction equation

HRID 826842 reaction equation
[Br:9][c:10]1[c:11]([Cl:20])[n:12][cH:13][c:14]([C:16]([F:17])([F:18])[F:19])[cH:15]1.[H-:7].[Na+:8].[O:22]1[CH2:23][CH2:24][CH2:25][CH2:26]1.[OH2:21].[OH:1][CH2:2][C:3]([F:4])([F:5])[F:6]>>[O:1]([CH2:2][C:3]([F:4])([F:5])[F:6])[c:11]1[c:10]([Br:9])[cH:15][c:14]([C:16]([F:17])([F:18])[F:19])[cH:13][n:12]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 962WaterHCID 64092,2,2-TrifluoroethanolHCID 8028TetrahydrofuranHCID 166653HydrideHCID 135360613-Bromo-2-chloro-5-(trifluoromethyl)pyridine

Product 1

HCID 220002003-Bromo-2-(2,2,2-trifluoroethoxy)-5-(trifluoromethyl)pyridine

Sources & evidence

ORD record
ord-5b47b2cba0344d969b44966afef18f8c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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