Hydrochloric Acid → 3-(1-Aminomethyl-6,7-dimethoxy-isoquinolin-4-yl)-1-benzyl-1-methyl-urea

HRID 826978Notes

Reaction equation

HRID 826978 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH2:8][c:9]1[n:10][cH:11][c:12]([NH:23][C:24](=[O:25])[N:26]([CH3:27])[CH2:28][c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:13]2[cH:14][c:15]([O:21][CH3:22])[c:16]([O:19][CH3:20])[cH:17][c:18]12)([CH3:5])([CH3:6])[CH3:35].[CH3:37][CH2:38][O:39][C:40]([CH3:41])=[O:42].[ClH:36]>>[NH2:7][CH2:8][c:9]1[n:10][cH:11][c:12]([NH:23][C:24](=[O:25])[N:26]([CH3:27])[CH2:28][c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:13]2[cH:14][c:15]([O:21][CH3:22])[c:16]([O:19][CH3:20])[cH:17][c:18]12

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8857Ethyl AcetateHCID 59341092[4-(3-Benzyl-3-methyl-ureido)-6,7-dimethoxy-isoquinolin-1-ylmethyl]-carbamic acid tert-butyl ester

Product 1

HCID 468471703-(1-Aminomethyl-6,7-dimethoxy-isoquinolin-4-yl)-1-benzyl-1-methyl-urea

Sources & evidence

ORD record
ord-e0849cc8a0074cdf8b80e8ae4b7c0b5d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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