Hydrochloric Acid → Tetrahydro-4-[[[1-[[4-(trifluoromethyl)phenyl]methoxy]-2-naphthalenyl]carbonyl]amino]-2H-thiopyran-4-carboxylic acid

HRID 827546Notes

Reaction equation

HRID 827546 reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:1][O:2][C:3](=[O:4])[C:5]1([NH:11][C:12](=[O:13])[c:14]2[c:15]([O:24][CH2:25][c:26]3[cH:27][cH:28][c:29]([C:32]([F:33])([F:34])[F:35])[cH:30][cH:31]3)[c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]3[cH:22][cH:23]2)[CH2:6][CH2:7][S:8][CH2:9][CH2:10]1.[CH3:44][OH:45].[ClH:36].[Na+:43].[OH-:42]>>[O:2]=[C:3]([OH:4])[C:5]1([NH:11][C:12](=[O:13])[c:14]2[c:15]([O:24][CH2:25][c:26]3[cH:27][cH:28][c:29]([C:32]([F:33])([F:34])[F:35])[cH:30][cH:31]3)[c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]3[cH:22][cH:23]2)[CH2:6][CH2:7][S:8][CH2:9][CH2:10]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 8028TetrahydrofuranHCID 68840611HCID 68840611, compound

Product 1

HCID 57831237Tetrahydro-4-[[[1-[[4-(trifluoromethyl)phenyl]methoxy]-2-naphthalenyl]carbonyl]amino]-2H-thiopyran-4-carboxylic acid

Sources & evidence

ORD record
ord-cceae31e4ba14dccb7f382f8de00a76f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…