Chloride → 7-chloro-1-(diphenylmethyl)-3-hydroxy-3-(6-hydroxy-2,3-dihydro-1-benzofuran-5-yl)-1,3-dihydro-2H-indol-2-one

HRID 827620Notes

Reaction equation

HRID 827620 reaction equation
[CH:12]([Mg+:13])([CH3:14])[CH3:15].[Cl-:11].[Cl:16][c:17]1[cH:18][cH:19][cH:20][c:21]2[c:25]1[N:24]([CH:26]([c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1)[c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1)[C:23](=[O:39])[C:22]2=[O:40].[O:1]1[CH2:2][CH2:3][c:4]2[c:5]1[cH:6][c:7]([OH:10])[cH:8][cH:9]2.[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1>>[O:1]1[CH2:2][CH2:3][c:4]2[c:5]1[cH:6][c:7]([OH:10])[c:8]([C:22]1([OH:40])[c:21]3[cH:20][cH:19][cH:18][c:17]([Cl:16])[c:25]3[N:24]([CH:26]([c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)[c:33]3[cH:34][cH:35][cH:36][cH:37][cH:38]3)[C:23]1=[O:39])[cH:9]2

Participants

6

Reactant 5

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 122365402,3-Dihydro-1-benzofuran-6-olHCID 673566457-chloro-1-(diphenylmethyl)-1H-indole-2,3-dioneHCID 178461726HCID 178461726, compound

Product 1

HCID 673566647-chloro-1-(diphenylmethyl)-3-hydroxy-3-(6-hydroxy-2,3-dihydro-1-benzofuran-5-yl)-1,3-dihydro-2H-indol-2-one

Sources & evidence

ORD record
ord-a9c2029e5508422aaeef45c13b69c3b3
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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