p-Toluenesulfonic acid → 2(5H)-Furanone, 3-(4-fluorophenyl)-4-[4-(methylsulfonyl)phenyl]-

HRID 827621Notes

Reaction equation

HRID 827621 reaction equation
[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH3:43][C:44]#[N:45].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][C:9](=[O:10])[O:11][CH2:12][C:13](=[O:14])[c:15]2[cH:16][cH:17][c:18]([S:21](=[O:22])(=[O:23])[CH3:24])[cH:19][cH:20]2)[cH:6][cH:7]1.[c:32]1([CH3:33])[cH:34][cH:35][c:36]([S:37]([OH:38])(=[O:39])=[O:40])[cH:41][cH:42]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]2=[C:13]([c:15]3[cH:16][cH:17][c:18]([S:21](=[O:22])(=[O:23])[CH3:24])[cH:19][cH:20]3)[CH2:12][O:11][C:9]2=[O:10])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 6101p-Toluenesulfonic acidHCID 6342AcetonitrileHCID 8471TriethylamineHCID 189338812-(4-(Methylsulfonyl)phenyl)-2-oxoethyl 2-(4-fluorophenyl)acetate

Product 1

HCID 108303942(5H)-Furanone, 3-(4-fluorophenyl)-4-[4-(methylsulfonyl)phenyl]-

Sources & evidence

ORD record
ord-6a46bdd40e6744c5ae2696b7e4e571a2
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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