1-Butanol → 3-{4-[(4-Methoxy-phenyl)-methyl-amino]-quinazolin-2-ylamino}-propan-1-ol

HRID 828213Notes

Reaction equation

HRID 828213 reaction equation
[CH2:32]([OH:33])[CH2:34][CH2:35][CH3:36].[CH:28]([Cl:29])([Cl:30])[Cl:31].[Cl:2][c:3]1[n:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[c:11]([N:13]([CH3:14])[c:15]2[cH:16][cH:17][c:18]([O:21][CH3:22])[cH:19][cH:20]2)[n:12]1.[ClH:1].[NH2:23][CH2:24][CH2:25][CH2:26][OH:27]>>[c:3]1([NH:23][CH2:24][CH2:25][CH2:26][OH:27])[n:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[c:11]([N:13]([CH3:14])[c:15]2[cH:16][cH:17][c:18]([O:21][CH3:22])[cH:19][cH:20]2)[n:12]1

Participants

6

Reactant 5

HCID 2631-ButanolHCID 313Hydrochloric AcidHCID 6212ChloroformHCID 90863-Amino-1-propanolHCID 117381122-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine

Product 1

HCID 592421093-{4-[(4-Methoxy-phenyl)-methyl-amino]-quinazolin-2-ylamino}-propan-1-ol

Sources & evidence

ORD record
ord-4c3bc839113e4d27b4db34ef2456432d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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