Hydrochloric Acid → 1-(3-Aminopropyl)-4-diphenylmethylpiperidine

HRID 828550Notes

Reaction equation

HRID 828550 reaction equation
[BH3:6].[ClH:30].[Na+:32].[O:1]1[CH2:2][CH2:3][CH2:4][CH2:5]1.[OH-:31].[c:7]1([CH:13]([CH:14]2[CH2:15][CH2:16][N:17]([CH2:20][CH2:21][C:22]#[N:23])[CH2:18][CH2:19]2)[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[cH:8][cH:9][cH:10][cH:11][cH:12]1>>[c:7]1([CH:13]([CH:14]2[CH2:15][CH2:16][N:17]([CH2:20][CH2:21][CH2:22][NH2:23])[CH2:18][CH2:19]2)[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[cH:8][cH:9][cH:10][cH:11][cH:12]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 6331BoraneHCID 8028TetrahydrofuranHCID 230041313-(4-Diphenylmethylpiperidin-1-yl)propionitrile

Product 1

HCID 230041171-(3-Aminopropyl)-4-diphenylmethylpiperidine

Sources & evidence

ORD record
ord-74f4060482304a1eb420545116cd29b5
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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