Dimethylformamide → 1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile
Reaction equation
[CH2:37]([Cl:38])[Cl:39].[CH3:9][CH2:10][N:11]([CH2:12][CH3:13])[CH2:14][CH3:15].[Cl:16][CH2:17][C:18](=[O:19])[N:20]1[CH:21]([C:25](=[O:26])[NH2:27])[CH2:22][CH2:23][CH2:24]1.[NH2:1][C:2]([CH:3]1[NH:4][CH2:5][CH2:6][CH2:7]1)=[O:8].[O:28]=[CH:29][N:30]([CH3:31])[CH3:32].[S:33]([Cl:34])([Cl:35])=[O:36]>>[Cl:16][CH2:17][C:18](=[O:19])[N:20]1[CH:21]([C:25]#[N:27])[CH2:22][CH2:23][CH2:24]1Participants
7
Sources & evidence
- ORD record
- ord-95f3aa4ff33c461eaea893c2d569ae5a
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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