Potassium Cation → 1-[4-(imidazo[1,2-a]pyridin-2-yloxy)phenyl]-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[n:8][c:9]3[n:10]([cH:11][cH:12][cH:13][cH:14]3)[cH:15]2)[cH:16][cH:17]1.[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:28][NH:29][CH:30]1[CH2:31][CH2:32][CH2:33][CH2:34][CH:35]1[NH:36][CH3:37].[Cu:44][I:45].[K+:38].[K+:39].[NH:18]1[C:19](=[O:27])[CH2:20][c:21]2[c:22]1[n:23][cH:24][cH:25][cH:26]2.[O-:40][C:41]([O-:42])=[O:43]>>[c:2]1([N:18]2[C:19](=[O:27])[CH2:20][c:21]3[c:22]2[n:23][cH:24][cH:25][cH:26]3)[cH:3][cH:4][c:5]([O:6][c:7]2[n:8][c:9]3[n:10]([cH:11][cH:12][cH:13][cH:14]3)[cH:15]2)[cH:16][cH:17]1Participants
8
Reactant 7
HCID 813Potassium Cation2×
HCID 8028Tetrahydrofuran
HCID 19660Carbonate Ion
HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)
HCID 5510741-N,2-N-dimethylcyclohexane-1,2-diamine
HCID 138640951,3-Dihydro-2H-pyrrolo(2,3-b)pyridin-2-one
HCID 679931672-(4-Bromophenoxy)imidazo[1,2-a]pyridineProduct 1
Sources & evidence
- ORD record
- ord-c440acc8dd0c4e5489d64b272dfa98d6
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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