Chloride → Ethyl 4-chloro-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate

HRID 830725Notes

Reaction equation

HRID 830725 reaction equation
[CH2:21]([N+:22]([CH2:23][CH3:24])([CH2:25][CH3:26])[CH2:27][CH3:28])[CH2:29][CH2:30][CH3:31].[CH3:32][C:33]#[N:34].[Cl-:20].[OH:1][c:2]1[c:3]([C:10](=[O:11])[O:12][CH2:13][CH3:14])[c:4](=[O:9])[nH:5][c:6]([CH3:8])[cH:7]1.[P:15]([Cl:16])([Cl:17])([Cl:18])=[O:19]>>[c:2]1([Cl:17])[c:3]([C:10](=[O:11])[O:12][CH2:13][CH3:14])[c:4](=[O:9])[nH:5][c:6]([CH3:8])[cH:7]1

Participants

6

Reactant 5

HCID 312ChlorideHCID 6342AcetonitrileHCID 24813Phosphorus oxychlorideHCID 457191-Butanaminium, N,N,N-triethyl-HCID 54676534Ethyl 2,4-dihydroxy-6-methylpyridine-3-carboxylate

Product 1

HCID 57859986Ethyl 4-chloro-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate

Sources & evidence

ORD record
ord-f5f777a822e64c28ac009a4b5f686299
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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