Formic Acid → benzyl N-(4-chloro-3-hydroxy-1-naphthalen-1-ylbutan-2-yl)carbamate

HRID 830799Notes

Reaction equation

HRID 830799 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH:12]([C:13]([CH2:14][Cl:15])=[O:16])[CH2:17][c:18]1[cH:19][cH:20][cH:21][c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]12.[CH2:28]([N:29]([CH2:30][CH3:31])[CH2:32][CH3:33])[CH3:34].[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[CH:35]([OH:36])=[O:37].[Cl:70][Rh+:71][C:72]1=[C:80]([CH3:81])[C:78]([CH3:79])=[C:76]([CH3:77])[C:73]1([CH3:74])[CH3:75].[c:44]1([CH3:45])[cH:46][cH:47][c:48]([S:49]([NH:50][CH:51]([c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[CH:58]([c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)[NH2:65])(=[O:66])=[O:67])[cH:68][cH:69]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH:12]([CH:13]([CH2:14][Cl:15])[OH:16])[CH2:17][c:18]1[cH:19][cH:20][cH:21][c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]12

Participants

7

Reactant 6

HCID 284Formic AcidHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 3608242N-(2-amino-1,2-diphenylethyl)-4-methylbenzenesulfonamideHCID 178425026HCID 178425026, compoundHCID 178523123benzyl N-(4-chloro-1-naphthalen-1-yl-3-oxobutan-2-yl)carbamate

Product 1

HCID 178523124benzyl N-(4-chloro-3-hydroxy-1-naphthalen-1-ylbutan-2-yl)carbamate

Sources & evidence

ORD record
ord-359aa04321aa4427a77a26308ac44022
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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