Tetrahydrofuran → 1-[4-[5-[(4-Fluorophenyl)methyl]thiophen-2-yl]but-3-en-2-yl]-1-hydroxyurea
Reaction equation
[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:23][CH:24]([CH2:25][AlH:26][CH2:27][CH:28]([CH3:29])[CH3:30])[CH3:31].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][c:9]2[cH:10][cH:11][c:12]([C:14]#[C:15][CH:16]([CH3:17])[N:18]([C:19](=[O:20])[NH2:21])[OH:22])[s:13]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][c:9]2[cH:10][cH:11][c:12]([CH:14]=[CH:15][CH:16]([CH3:17])[N:18]([C:19](=[O:20])[NH2:21])[OH:22])[s:13]2)[cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-551fbc207c0442258d0efecab8479d17
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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