Pyridine → 1-(4-methoxy-1H-pyrrolo[2,3-c]pyridin-7-yl)-1H-1,2,4-triazole-3-carbonitrile

HRID 831654Notes

Reaction equation

HRID 831654 reaction equation
[CH3:26][CH2:27][O:28][C:29]([CH3:30])=[O:31].[Cl:1][c:2]1[n:3][cH:4][c:5]([O:11][CH3:12])[c:6]2[c:7]1[nH:8][cH:9][cH:10]2.[Cu:32][I:33].[cH:20]1[cH:21][cH:22][n:23][cH:24][cH:25]1.[nH:13]1[n:14][c:15]([C:18]#[N:19])[n:16][cH:17]1>>[c:2]1(-[n:13]2[n:14][c:15]([C:18]#[N:19])[n:16][cH:17]2)[n:3][cH:4][c:5]([O:11][CH3:12])[c:6]2[c:7]1[nH:8][cH:9][cH:10]2

Participants

6

Reactant 5

HCID 1049PyridineHCID 8857Ethyl AcetateHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 159870137-Chloro-4-methoxy-1H-pyrrolo[2,3-c]pyridineHCID 178510603HCID 178510603, compound

Product 1

HCID 580260371-(4-methoxy-1H-pyrrolo[2,3-c]pyridin-7-yl)-1H-1,2,4-triazole-3-carbonitrile

Sources & evidence

ORD record
ord-8f14a106ea174e9eaa306845a1a9bdf3
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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