Tetrahydrofuran → 1-(4-Methoxy-benzyl)-2,2-dimethyl-piperazine

HRID 831809Notes

Reaction equation

HRID 831809 reaction equation
[Al+3:2].[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:7][O:8][c:9]1[cH:10][cH:11][c:12]([CH2:13][N:14]2[C:15]([CH3:21])([CH3:22])[C:16](=[O:20])[NH:17][CH2:18][CH2:19]2)[cH:23][cH:24]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3]>>[CH3:7][O:8][c:9]1[cH:10][cH:11][c:12]([CH2:13][N:14]2[C:15]([CH3:21])([CH3:22])[CH2:16][NH:17][CH2:18][CH2:19]2)[cH:23][cH:24]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 669145564-(4-Methoxybenzyl)-3,3-dimethyl-piperazin-2-one

Product 1

HCID 635966481-(4-Methoxy-benzyl)-2,2-dimethyl-piperazine

Sources & evidence

ORD record
ord-614abc137c3648bc8f225b04153d3a03
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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