Hydrochloric Acid → 6-Bromo-4-iodoquinoline

HRID 831998Notes

Reaction equation

HRID 831998 reaction equation
[Br:2][c:3]1[cH:4][c:5]2[c:6]([Cl:13])[cH:7][cH:8][n:9][c:10]2[cH:11][cH:12]1.[C:16](#[N:17])[CH2:18][CH3:19].[ClH:1].[I-:15].[K+:26].[K+:27].[Na+:14].[Na+:24].[Na+:25].[O-:28][C:29]([O-:30])=[O:31].[S:20]([O-:21])([O-:22])=[O:23]>>[Br:2][c:3]1[cH:4][c:5]2[c:6]([I:15])[cH:7][cH:8][n:9][c:10]2[cH:11][cH:12]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 923Sodium ion3×HCID 1099SulfiteHCID 7854PropionitrileHCID 19660Carbonate IonHCID 30165Iodide IonHCID 51395376-Bromo-4-chloroquinoline

Product 1

HCID 177505956-Bromo-4-iodoquinoline

Sources & evidence

ORD record
ord-b9f3d52ac9374994abaefae89db248c6
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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