Sodium ion → (4,4-Difluorocyclohexyl)methanol

HRID 832442Notes

Reaction equation

HRID 832442 reaction equation
[Al+3:15].[F:1][C:2]1([F:13])[CH2:3][CH2:4][CH:5]([C:8](=[O:9])[O:10][CH2:11][CH3:12])[CH2:6][CH2:7]1.[H-:14].[H-:17].[H-:18].[H-:19].[Li+:16].[Na+:21].[O:22]1[CH2:23][CH2:24][CH2:25][CH2:26]1.[OH-:20]>>[F:1][C:2]1([F:13])[CH2:3][CH2:4][CH:5]([CH2:8][OH:9])[CH2:6][CH2:7]1

Participants

8

Reactant 7

HCID 923Sodium ionHCID 961HydroxideHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 2779138Ethyl-4,4-difluorocyclohexane carboxylate

Product 1

HCID 21184133(4,4-Difluorocyclohexyl)methanol

Sources & evidence

ORD record
ord-54d25b3ffbf545a7bbdd0acb0060cb29
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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