Dimethylformamide → 5-methyl-6-(pyrrolidine-1-carbonyl)thieno[2,3-d]pyrimidin-4(3H)-one

HRID 832480Notes

Reaction equation

HRID 832480 reaction equation
[CH2:19]1[CH2:20][CH2:21][NH:22][CH2:23]1.[CH3:1][c:2]1[c:3]([C:12](=[O:13])[OH:14])[s:4][c:5]2[n:6][cH:7][nH:8][c:9](=[O:11])[c:10]12.[O:24]=[CH:25][N:26]([CH3:27])[CH3:28].[S:15]([Cl:16])([Cl:17])=[O:18]>>[CH3:1][c:2]1[c:3]([C:12](=[O:14])[N:22]2[CH2:21][CH2:20][CH2:19][CH2:23]2)[s:4][c:5]2[n:6][cH:7][nH:8][c:9](=[O:11])[c:10]12

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 31268PyrrolidineHCID 4058025-methyl-4-oxo-3H,4H-thieno[2,3-d]pyrimidine-6-carboxylic acid

Product 1

HCID 598428315-methyl-6-(pyrrolidine-1-carbonyl)thieno[2,3-d]pyrimidin-4(3H)-one

Sources & evidence

ORD record
ord-cdaeaf4170f54a138218f0fe421bb45d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…