Hydrochloric Acid → hexahydro-1-[2-(4-methoxyphenyl)ethyl]-4H-azepin-4-one

HRID 833005Notes

Reaction equation

HRID 833005 reaction equation
[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][N:11]2[CH2:12][CH2:13][C:14]3([O:15][CH2:18][CH2:17][O:16]3)[CH2:19][CH2:20][CH2:21]2)[cH:7][cH:8]1.[ClH:28].[K+:22].[K+:23].[O-:24][C:25]([O-:26])=[O:27]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][N:11]2[CH2:12][CH2:13][C:14](=[O:15])[CH2:19][CH2:20][CH2:21]2)[cH:7][cH:8]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 8028TetrahydrofuranHCID 19660Carbonate IonHCID 692829498-[2-(4-Methoxyphenyl)ethyl]-1,4-dioxa-8-azaspiro[4.6]undecane

Product 1

HCID 69282946hexahydro-1-[2-(4-methoxyphenyl)ethyl]-4H-azepin-4-one

Sources & evidence

ORD record
ord-e466fbd296c04efea64a4c09b15f38cf
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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