Acetone → N-{5-[2-(4-bromophenyl)ethyl]-2,2-dimethyl-1,3-dioxan-5-yl}acetamide

HRID 833394Notes

Reaction equation

HRID 833394 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH2:9][C:10]([CH2:11][OH:12])([CH2:13][OH:14])[NH:15][C:16]([CH3:17])=[O:18])[cH:6][cH:7]1.[CH3:19][O:20][C:21]([CH3:22])([CH3:23])[O:24][CH3:25].[CH3:37][C:38](=[O:39])[CH3:40].[c:26]1([CH3:27])[cH:28][cH:29][c:30]([S:31]([OH:32])(=[O:33])=[O:34])[cH:35][cH:36]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH2:9][C:10]2([NH:15][C:16]([CH3:17])=[O:18])[CH2:11][O:12][C:21]([CH3:22])([CH3:23])[O:14][CH2:13]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 180AcetoneHCID 6101p-Toluenesulfonic acidHCID 64952,2-DimethoxypropaneHCID 57624600N-[3-(4-bromophenyl)-1,1-bis(hydroxymethyl)propyl]acetamide

Product 1

HCID 46202882N-{5-[2-(4-bromophenyl)ethyl]-2,2-dimethyl-1,3-dioxan-5-yl}acetamide

Sources & evidence

ORD record
ord-ce4fc6048503489391ff5f07dd0566d3
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…