Tetrahydrofuran → methyl 3-bromo-4-[N'-(2-methylphenyl)ureido]phenylacetate

HRID 833396Notes

Reaction equation

HRID 833396 reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:14][c:15]1[c:16]([N:21]=[C:22]=[O:23])[cH:17][cH:18][cH:19][cH:20]1.[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[NH2:1][c:2]1[c:3]([Br:13])[cH:4][c:5]([CH2:8][C:9](=[O:10])[O:11][CH3:12])[cH:6][cH:7]1>>[NH:1]([c:2]1[c:3]([Br:13])[cH:4][c:5]([CH2:8][C:9](=[O:10])[O:11][CH3:12])[cH:6][cH:7]1)[C:22]([NH:21][c:16]1[c:15]([CH3:14])[cH:20][cH:19][cH:18][cH:17]1)=[O:23]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 691942-Tolyl isocyanateHCID 15462911Methyl 2-(4-amino-3-bromophenyl)acetate

Product 1

HCID 23512369methyl 3-bromo-4-[N'-(2-methylphenyl)ureido]phenylacetate

Sources & evidence

ORD record
ord-336734fbe97944f8bc4e7111a2339d03
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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