2-Pentanol → 4-(4-Bromo-2-fluoro-5-hydroxyanilino)-6,7-dimethoxyquinoline

HRID 834424Notes

Reaction equation

HRID 834424 reaction equation
[Br:16][c:17]1[cH:18][c:19]([F:25])[c:20]([NH2:21])[cH:22][c:23]1[OH:24].[CH3:36][CH:37]([OH:38])[CH2:39][CH2:40][CH3:41].[Cl:1][c:2]1[cH:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH3:15])[c:9]([O:12][CH3:13])[cH:10][c:11]12.[Cl:26][c:27]1[c:28]([OH:29])[cH:30][c:31]([NH2:32])[c:33]([F:34])[cH:35]1>>[c:2]1([NH:21][c:20]2[c:19]([F:25])[cH:18][c:17]([Br:16])[c:23]([OH:24])[cH:22]2)[cH:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH3:15])[c:9]([O:12][CH3:13])[cH:10][c:11]12

Participants

5

Reactant 4

HCID 223862-PentanolHCID 1586545-Amino-2-chloro-4-fluorophenolHCID 4596104-Chloro-6,7-dimethoxyquinolineHCID 109656515-Amino-2-bromo-4-fluorophenol

Product 1

HCID 179389704-(4-Bromo-2-fluoro-5-hydroxyanilino)-6,7-dimethoxyquinoline

Sources & evidence

ORD record
ord-65ab617efb4a4eb89ecc9bb7e01bd6b4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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