Chloride → 4-(4-Ethylphenyl)-1-methyl-piperidine

HRID 834477Notes

Reaction equation

HRID 834477 reaction equation
[Al+3:15].[CH2:18]([CH3:19])[Br:20].[CH3:1][N:2]1[CH2:3][CH2:4][CH:5]([c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[CH2:6][CH2:7]1.[Cl-:14].[Cl-:16].[Cl-:17].[Cl:23][CH2:24][C:25]([Cl:26])([Cl:27])[Cl:28].[Na+:22].[OH-:21]>>[CH3:1][N:2]1[CH2:3][CH2:4][CH:5]([c:8]2[cH:9][cH:10][c:11]([CH2:18][CH3:19])[cH:12][cH:13]2)[CH2:6][CH2:7]1

Participants

8

Reactant 7

HCID 312Chloride3×HCID 923Sodium ionHCID 961HydroxideHCID 6332Ethyl BromideHCID 124181,1,1,2-TetrachloroethaneHCID 104727Aluminum CationHCID 202391Piperidine, 1-methyl-4-phenyl-

Product 1

HCID 128501084-(4-Ethylphenyl)-1-methyl-piperidine

Sources & evidence

ORD record
ord-b122c8aa4f6c4bc89fa88c1530f47bbb
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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